Using mass spectrometry analysis, only trace amounts of previously characterized oxPS species were found. Given the oxidative capacity of the neutrophil NADPH oxidase, we sought to identify oxPS signaling species in stimulated neutrophils. Oxidation of PS fatty acyl groups (oxPS) during apoptosis reportedly mediates recognition through scavenger receptors. Exofacial phosphatidylserine (PS) is an important ligand mediating apoptotic cell clearance by phagocytes.
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